commit/galaxy-central: jgoecks: Trackster: add histogram mode to feature tracks so that user can generate coverage histogram at any level of data. Refactor overlap computation out of modules for now since it's a general purpose method used in multiple modules.
1 new changeset in galaxy-central: http://bitbucket.org/galaxy/galaxy-central/changeset/33fe59c762a8/ changeset: r5369:33fe59c762a8 user: jgoecks date: 2011-04-12 20:40:59 summary: Trackster: add histogram mode to feature tracks so that user can generate coverage histogram at any level of data. Refactor overlap computation out of modules for now since it's a general purpose method used in multiple modules. affected #: 1 file (4.6 KB) --- a/static/scripts/trackster.js Tue Apr 12 12:10:48 2011 -0400 +++ b/static/scripts/trackster.js Tue Apr 12 14:40:59 2011 -0400 @@ -14,6 +14,50 @@ return target; }; +/** + * Compute the type of overlap between two regions. They are assumed to be on the same chrom/contig. + * The overlap is computed relative to the second region; hence, OVERLAP_START indicates that the first + * region overlaps the start (but not the end) of the second region. + */ +var BEFORE = 1001, CONTAINS = 1002, OVERLAP_START = 1003, OVERLAP_END = 1004, CONTAINED_BY = 1005, AFTER = 1006; +var compute_overlap = function(first_region, second_region) { + var + first_start = first_region[0], first_end = first_region[1], + second_start = second_region[0], second_end = second_region[1], + overlap; + if (first_start < second_start) { + if (first_end < second_start) { + overlap = BEFORE; + } + else if (first_end <= second_end) { + overlap = OVERLAP_START; + } + else { // first_end > second_end + overlap = CONTAINS; + } + } + else { // first_start >= second_start + if (first_start > second_end) { + overlap = AFTER; + } + else if (first_end <= second_end) { + overlap = CONTAINED_BY; + } + else { + overlap = OVERLAP_END; + } + } + + return overlap; +}; +/** + * Returns true if regions overlap. + */ +var is_overlap = function(first_region, second_region) { + var overlap = compute_overlap(first_region, second_region); + return (overlap !== BEFORE && overlap !== AFTER); +}; + // Encapsulate -- anything to be availabe outside this block is added to exports var trackster_module = function(require, exports){ @@ -98,7 +142,7 @@ $(this).insertBefore( children.get( i ) ); } }); -} +}; /** * Calculates step for slider with a given min, max. @@ -106,7 +150,7 @@ var get_slider_step = function(min, max) { var range = max - min; return (range <= 2 ? 0.01 : (range <= 100 ? 1 : (range <= 1000 ? 5 : 10))); -} +}; /** * Init constants & functions used throughout trackster. @@ -142,7 +186,7 @@ function round_1000(num) { return Math.round(num * 1000) / 1000; -} +}; /** * Generic cache that handles key/value pairs. @@ -2061,14 +2105,14 @@ } }); -var FeatureTrack = function (name, view, hda_ldda, dataset_id, prefs, filters, tool, parent_track) { +var FeatureTrack = function(name, view, hda_ldda, dataset_id, prefs, filters, tool, parent_track) { // // Preinitialization: do things that need to be done before calling Track and TiledTrack // initialization code. // var track = this; this.track_type = "FeatureTrack"; - this.display_modes = ["Auto", "Dense", "Squish", "Pack"]; + this.display_modes = ["Auto", "Histogram", "Dense", "Squish", "Pack"]; // Define and restore track configuration. this.track_config = new TrackConfig( { track: this, @@ -2143,6 +2187,84 @@ return inc_slots.slot_features( features ); }, /** + * Given feature data, returns summary tree data. Feature data must be sorted by start + * position. Return value is a dict with keys 'data', 'delta' (bin size) and 'max.' Data + * is a two-item list; first item is bin start, second is bin's count. + */ + get_summary_tree_data: function(data, low, high, bin_size) { + var num_bins = Math.floor((high - low)/bin_size), + bins = [], + max_count = 0; + + /* + // For debugging: + for (var i = 0; i < data.length; i++) + console.log("\t", data[i][1], data[i][2], data[i][3]); + */ + + // + // Loop through bins, counting data for each interval. + // + var data_index_start = 0, + data_index = 0, + data_interval, + bin_index = 0, + bin_interval = [], + cur_bin, + overlap; + + // Set bin interval. + var set_bin_interval = function(interval, low, bin_index, bin_size) { + interval[0] = low + bin_index * bin_size; + interval[1] = low + (bin_index + 1) * bin_size; + }; + + // Loop through bins, data to compute bin counts. Only compute bin counts as long + // as there is data. + while (bin_index < num_bins && data_index_start !== data.length) { + // Find next bin that has data. + var bin_has_data = false; + for (; bin_index < num_bins && !bin_has_data; bin_index++) { + set_bin_interval(bin_interval, low, bin_index, bin_size); + // Loop through data and break if data found that goes in bin. + for (data_index = data_index_start; data_index < data.length; data_index++) { + data_interval = data[data_index].slice(1, 3); + if (is_overlap(data_interval, bin_interval)) { + bin_has_data = true; + break; + } + } + // Break from bin loop if this bin has data. + if (bin_has_data) { + break; + } + } + + // Set start index to current data, which is the first to overlap with this bin + // and perhaps with later bins. + data_start_index = data_index; + + // Count intervals that overlap with bin. + bins[bins.length] = cur_bin = [bin_interval[0], 0]; + for (; data_index < data.length; data_index++) { + data_interval = data[data_index].slice(1, 3); + if (is_overlap(data_interval, bin_interval)) { + cur_bin[1]++; + } + else { break; } + } + + // Update max count. + if (cur_bin[1] > max_count) { + max_count = cur_bin[1]; + } + + // Go to next bin. + bin_index++; + } + return {max: max_count, delta: bin_size, data: bins}; + }, + /** * Draw FeatureTrack tile. */ draw_tile: function(result, resolution, tile_index, parent_element, w_scale, ref_seq) { @@ -2156,7 +2278,7 @@ left_offset = this.left_offset, slots, required_height; - + // Set display mode if Auto. if (mode === "Auto") { if (result.dataset_type === "summary_tree") { @@ -2211,6 +2333,35 @@ // Canvas element is returned return canvas; } + + // Drawing coverage histogram. This is different from summary tree because data can feature + // details, but user has requested a histogram. + if (mode === "Histogram") { + // Set height of parent_element + required_height = this.summary_draw_height; + parent_element.parent().css("height", Math.max(this.height_px, required_height) + "px"); + // Add label to container div showing maximum count + // TODO: this shouldn't be done at the tile level + this.container_div.find(".yaxislabel").remove(); + var max_label = $("<div />").addClass('yaxislabel'); + max_label.text( result.max ); + max_label.css({ position: "absolute", top: "22px", left: "10px" }); + max_label.prependTo(this.container_div); + // Create canvas + var canvas = this.view.canvas_manager.new_canvas(); + canvas.width = width + left_offset; + // Extra padding at top of summary tree + canvas.height = required_height + SUMMARY_TREE_TOP_PADDING; + // Paint summary tree into canvas. + var binned_data = this.get_summary_tree_data(result.data, tile_low, tile_high, 200); + var painter = new painters.SummaryTreePainter(binned_data, tile_low, tile_high, this.prefs); + var ctx = canvas.getContext("2d"); + // Deal with left_offset by translating + ctx.translate(left_offset, SUMMARY_TREE_TOP_PADDING); + painter.draw(ctx, width, required_height); + // Canvas element is returned + return canvas; + } // Start dealing with row-by-row tracks @@ -3090,43 +3241,6 @@ } }); -/** - * Compute the type of overlap between two regions. They are assumed to be on the same chrom/contig. - * The overlap is computed relative to the second region; hence, OVERLAP_START indicates that the first - * region overlaps the start (but not the end) of the second region. - */ -var NO_OVERLAP = 1001, CONTAINS = 1002, OVERLAP_START = 1003, OVERLAP_END = 1004, CONTAINED_BY = 1005; -var compute_overlap = function(first_region, second_region) { - var - first_start = first_region[0], first_end = first_region[1], - second_start = second_region[0], second_end = second_region[1], - overlap; - if (first_start < second_start) { - if (first_end < second_start) { - overlap = NO_OVERLAP; - } - else if (first_end <= second_end) { - overlap = OVERLAP_START; - } - else { // first_end > second_end - overlap = CONTAINS; - } - } - else { // first_start >= second_start - if (first_start > second_end) { - overlap = NO_OVERLAP; - } - else if (first_end <= second_end) { - overlap = CONTAINED_BY; - } - else { - overlap = OVERLAP_END; - } - } - - return overlap; -} - var ReadPainter = function( data, view_start, view_end, prefs, mode, ref_seq ) { FeaturePainter.call( this, data, view_start, view_end, prefs, mode ); this.ref_seq = ref_seq; @@ -3208,8 +3322,7 @@ case "S": // Soft clipping. case "M": // Match. case "=": // Equals. - var seq_tile_overlap = compute_overlap([seq_start, seq_start + cig_len], tile_region); - if (seq_tile_overlap !== NO_OVERLAP) { + if (is_overlap([seq_start, seq_start + cig_len], tile_region)) { // Draw. var seq = orig_seq.slice(seq_offset, seq_offset + cig_len); if (gap > 0) { @@ -3258,11 +3371,9 @@ case "I": // Insertion. // Check to see if sequence should be drawn at all by looking at the overlap between // the sequence region and the tile region. - var - seq_tile_overlap = compute_overlap([seq_start, seq_start + cig_len], tile_region), - insert_x_coord = s_start - gap; + var insert_x_coord = s_start - gap; - if (seq_tile_overlap !== NO_OVERLAP) { + if (is_overlap([seq_start, seq_start + cig_len], tile_region)) { var seq = orig_seq.slice(seq_offset, seq_offset + cig_len); // Insertion point is between the sequence start and the previous base: (-gap) moves // back from sequence start to insertion point. 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