Hi Nate, all I would like to add my own version of the problem to this. I, or rather my (inherited) Galaxy instance (which should be running 15.05+, how do I find out?), have/s similar symptoms as Richard's did. In my case it only occurs to a single user and we are not able to execute the "Saved Histories" command any more. Galaxy will fail with Proxy Error The proxy server received an invalid response from an upstream server. The proxy server could not handle the request GET /history/list. Reason: Error reading from remote server Due to some problem with the psql-client I cannot find the potential perpetrators (my user has lots of bam files in various histories) and since he cannot switch histories, we cannot even update the metadata for his datasets. Is there a possibility to do that via the API? Any insight/help would be greatly appreciated! Cheers Christian On 08/07/15 21:04, Poole, Richard wrote: I am having trouble right now with my own personal account on my production server. Grid refreshes are taking a huge amount of time (e.g. when viewing ‘saved histories’ or even generating the dataset list for a single history). My account is very full of data (1TB), could it be this? There are no obvious messages in the logs though so I am a bit stumped as to why.I do not have the same trouble when impersonating other users with fairly full accounts. Perhaps a database issue (I do not know how to ‘cleanup’ the database or indeed Galaxy user accounts). Any thoughts? -- Dr. Christian Schudoma Bioinformatics Support Officer Bioinformatics Group The Sainsbury Laboratory Norwich Research Park Norwich NR4 7UH United Kingdom ****************************** +44 (0) 1603 450 601 christian.schudoma@tsl.ac.uk<mailto:christian.schudoma@tsl.ac.uk>