Dear galaxy-dev-list, I am trying to use new-style job configuration whith a load-balancing on 2 web servers and 2 job hanlders. I have configured load balancing as follows (universe_wsgi.ini): # Configuration of the internal HTTP server. [server:web0] use = egg:Paste#http port = 8083 host = 127.0.0.1 use_threadpool = true threadpool_workers = 7 [server:web1] use = egg:Paste#http port = 8082 host = 127.0.0.1 use_threadpool = true threadpool_workers = 7 [server:manager] use = egg:Paste#http port = 8079 host = 127.0.0.1 use_threadpool = true threadpool_workers = 5 [server:handler0] use = egg:Paste#http port = 8090 host = 127.0.0.1 use_threadpool = true threadpool_workers = 5 [server:handler1] use = egg:Paste#http port = 8091 host = 127.0.0.1 use_threadpool = true threadpool_workers = 5 This configuration works fine (manager.log): galaxy.jobs.manager DEBUG 2013-04-23 12:20:22,901 Starting job handler galaxy.jobs.runners DEBUG 2013-04-23 12:20:22,902 Starting 5 LocalRunner workers galaxy.jobs DEBUG 2013-04-23 12:20:22,904 Loaded job runner 'galaxy.jobs.runners.local:LocalJobRunner' as 'local' galaxy.jobs.runners DEBUG 2013-04-23 12:20:22,909 Starting 3 LWRRunner workers galaxy.jobs DEBUG 2013-04-23 12:20:22,911 Loaded job runner 'galaxy.jobs.runners.lwr:LwrJobRunner' as 'lwr' galaxy.jobs DEBUG 2013-04-23 12:20:22,911 Legacy destination with id 'local:///', url 'local:///' converted, got params: galaxy.jobs.handler DEBUG 2013-04-23 12:20:22,911 Loaded job runners plugins: lwr:local galaxy.jobs.handler INFO 2013-04-23 12:20:22,912 job handler stop queue started galaxy.jobs.handler INFO 2013-04-23 12:20:22,919 job handler queue started To use new-style job configuration I have create the following job_conf.xml: <?xml version="1.0"?> <!-- A sample job config that explicitly configures job running the way it is configured by default (if there is no explicit config). --> <job_conf> <plugins> <plugin id="local" type="runner" load="galaxy.jobs.runners.local:LocalJobRunner"/> </plugins> <handlers default="handlers"> <!-- Additional job handlers - the id should match the name of a [server:<id>] in universe_wsgi.ini. --> <handler id="server:web0" tags="handlers"/> <handler id="server:web1" tags="handlers"/> </handlers> <destinations default="local"> <destination id="local" runner="local"/> </destinations> </job_conf> When I restart the instance the manager.log outputs: galaxy.jobs DEBUG 2013-05-02 17:25:28,402 Loading job configuration from ./job_conf.xml galaxy.jobs DEBUG 2013-05-02 17:25:28,402 Read definition for handler 'server:web0' galaxy.jobs DEBUG 2013-05-02 17:25:28,403 Read definition for handler 'server:web1' galaxy.jobs DEBUG 2013-05-02 17:25:28,403 <handlers> default set to child with id or tag 'handlers' galaxy.jobs DEBUG 2013-05-02 17:25:28,403 <destinations> default set to child with id or tag 'local' galaxy.jobs DEBUG 2013-05-02 17:25:28,403 Done loading job configuration So everything seems fine but when I try to run a tool, the corresponding job is in permanent waiting status (gray color in history). I think I have missed something in the configuration process, Thanks for your help, Olivier