Jeremy, I have observed the same. My python version is newer 2.6.4 (r264:75706, Dec 7 2009) so that should be ok. There are however javascript errors on win7x64 ie8. I paste the error details below (my translation from Dutch). These errors are there onload and the options link does not work at all. Any help appreciated. Alex Error details webpage Useragent: Mozilla/4.0 (compatible; MSIE 8.0; Windows NT 6.1; WOW64; Trident/4.0; SLCC2; .NET CLR 2.0.50727; .NET CLR 3.5.30729; .NET CLR 3.0.30729; Media Center PC 6.0; .NET4.0C; InfoPath.3) Timestamp: Thu, 21 Oct 2010 06:28:46 UTC Message: Id, charset or number expected Line: 444 Char: 9 Code: 0 URI: http://galaxy01:8080/ Van: galaxy-dev-bounces@lists.bx.psu.edu [mailto:galaxy-dev-bounces@lists.bx.psu.edu] Namens Jeremy Goecks Verzonden: woensdag 20 oktober 2010 22:58 Aan: zhe@lanl.gov CC: galaxy-dev@bx.psu.edu Onderwerp: Re: [galaxy-dev] Search tools button My python version is 2.4.3. That could be the problem. Yes, that's the problem. You'll need to upgrade to Python 2.5 or higher to get tool search. BTW, where is "panel/frame"? I did not find it. The main Galaxy interface has three iframe HTML objects: the tools menu, the history, and the workspace (middle frame). In Galaxy, we refer to these as panels; because each iframe has different source code and Javascript, you often have to look in a particular frame to find Javascript issues. That said, I'm confident that your problem is your Python version. Thanks, J.