Hi I have been tasked with getting a Galaxy server up and running for a group at work. 1. No-one can tell me how many users (concurrent or otherwise) there will be 2. Most of the analyses will be NGS. 3. Tools will be developed in-house but we will use public domain tools also. 4. There will be a guy running the server/developing tools pretty much full time. I have two favoured solutions at the moment: 1. A pipeline processor ( 64 Core, 512G Ram, with DAS of about 150TB ), and a Web server to act as frontend and database server, and another, smaller box for a total install of galaxy, but doing only the development work. 2. An all-in-one server with 128 Cores, 1TB ram, DAS storage of 150TB, and development work done on a VM. Any input would be hepfull. Thanks Shane