Hi, Since Galaxy need to be restarted sometime (load datatype, add ressources in .loc, apply changes in the galaxy.ini), is anybody of you have solutions to restart it without interrupt the service? We are now using nginx, uwsgi and supervisord. My hope is to split the Galaxy process in two group (1 uwsgi and 2 job handlers per group). That way, we will be able to restart the group1 and then the group2. I was planning to set the 2 uwsgi servers and delegate the load balancing to ngnix (https://www.nginx.com/resources/admin-guide/load-balancer/ <https://www.nginx.com/resources/admin-guide/load-balancer/>) But maybe, some of you already implemented that and can provide me some advices or warnings. The job handler part seems easier to deal with --server-name=handler1_%(process_num)s --server-name=handler2_%(process_num)s Thanks by advance Gildas ----------------------------------------------------------------- Gildas Le Corguillé - Bioinformatician/Bioanalyste Plateform ABiMS (Analyses and Bioinformatics for Marine Science) http://abims.sb-roscoff.fr <http://abims.sb-roscoff.fr/> Member of the Workflow4Metabolomics project http://workflow4metabolomics.org <http://workflow4metabolomics.org/> Station Biologique de Roscoff - UPMC/CNRS - FR2424 Place Georges Teissier 29680 Roscoff FRANCE tel: +33 2 98 29 23 81 ------------------------------------------------------------------