On Monday, December 10, 2012, Jeremy Goecks wrote:
 

Decompress and unpack the file and you'll find the relevant files (though everything now has extensions with p* rather than n*); add an entry to blastdb pointing to the directory with these files and you should be good to go.

J.

Not quite -  blastdb.loc is for nucleotide databases only (needed for megablast), and NR is proteins. For that use blastdb_p.loc and blastp or blastx from the NCBI BLAST+ wrappers.

Peter