Hi Galaxy Devs,
I posted this question on biostars but didn't get an answer so I'll try here:
I just tried upgrading my local instance of Galaxy from 15.10 to 16.01. When I start it up I get an error. Does anyone have any suggestions?
galaxy@galaxy galaxy$ sh run.sh
Activating virtualenv at .venv
DEPRECATION: Python 2.6 is no longer supported by the Python core team, please upgrade your Python. A future version of pip will drop support for Python 2.6
Ignoring indexes: https://pypi.python.org/simple
/opt/galaxy/.venv/lib/python2.6/site-packages/pip/_vendor/requests/packages/urllib3/util/ssl_.py:315: SNIMissingWarning: An HTTPS request has been made, but the SNI (Subject Name Indication) extension to TLS is not available on this platform. This may cause the server to present an incorrect TLS certificate, which can cause validation failures. For more information, see https://urllib3.readthedocs.org/en/latest/security.html#snimissingwarning.
  SNIMissingWarning
/opt/galaxy/.venv/lib/python2.6/site-packages/pip/_vendor/requests/packages/urllib3/util/ssl_.py:120: InsecurePlatformWarning: A true SSLContext object is not available. This prevents urllib3 from configuring SSL appropriately and may cause certain SSL connections to fail. For more information, see https://urllib3.readthedocs.org/en/latest/security.html#insecureplatformwarning.
  InsecurePlatformWarning
Requirement already up-to-date: pip==8.0.2+gx2 in ./.venv/lib/python2.6/site-packages
DEPRECATION: Python 2.6 is no longer supported by the Python core team, please upgrade your Python. A future version of pip will drop support for Python 2.6
Requirement already satisfied (use --upgrade to upgrade): bx-python==0.7.3 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 2))
Requirement already satisfied (use --upgrade to upgrade): MarkupSafe==0.23 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 3))
Requirement already satisfied (use --upgrade to upgrade): PyYAML==3.11 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 4))
Requirement already satisfied (use --upgrade to upgrade): SQLAlchemy==1.0.8 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 5))
Requirement already satisfied (use --upgrade to upgrade): mercurial==3.4.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 7))
Requirement already satisfied (use --upgrade to upgrade): numpy==1.9.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 8))
Requirement already satisfied (use --upgrade to upgrade): pycrypto==2.6.1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 9))
Requirement already satisfied (use --upgrade to upgrade): Paste==2.0.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 16))
Requirement already satisfied (use --upgrade to upgrade): PasteDeploy==1.5.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 17))
Requirement already satisfied (use --upgrade to upgrade): docutils==0.12 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 18))
Requirement already satisfied (use --upgrade to upgrade): wchartype==0.1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 19))
Requirement already satisfied (use --upgrade to upgrade): repoze.lru==0.6 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 20))
Requirement already satisfied (use --upgrade to upgrade): Routes==2.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 21))
Requirement already satisfied (use --upgrade to upgrade): WebOb==1.4.1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 22))
Requirement already satisfied (use --upgrade to upgrade): WebHelpers==1.3 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 23))
Requirement already satisfied (use --upgrade to upgrade): Mako==1.0.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 24))
Requirement already satisfied (use --upgrade to upgrade): pytz==2015.4 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 25))
Requirement already satisfied (use --upgrade to upgrade): Babel==2.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 26))
Requirement already satisfied (use --upgrade to upgrade): Beaker==1.7.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 27))
Requirement already satisfied (use --upgrade to upgrade): Cheetah==2.4.4 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 30))
Requirement already satisfied (use --upgrade to upgrade): Markdown==2.6.3 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 31))
Requirement already satisfied (use --upgrade to upgrade): bioblend==0.6.1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 34))
Requirement already satisfied (use --upgrade to upgrade): boto==2.38.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 35))
Requirement already satisfied (use --upgrade to upgrade): requests==2.8.1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 36))
Requirement already satisfied (use --upgrade to upgrade): requests-toolbelt==0.4.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 37))
Requirement already satisfied (use --upgrade to upgrade): kombu==3.0.30 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 40))
Requirement already satisfied (use --upgrade to upgrade): amqp==1.4.8 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 41))
Requirement already satisfied (use --upgrade to upgrade): anyjson==0.3.3 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 42))
Requirement already satisfied (use --upgrade to upgrade): sqlalchemy-migrate==0.10.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 45))
Requirement already satisfied (use --upgrade to upgrade): decorator==4.0.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 46))
Requirement already satisfied (use --upgrade to upgrade): Tempita==0.5.3dev in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 47))
Requirement already satisfied (use --upgrade to upgrade): sqlparse==0.1.16 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 48))
Requirement already satisfied (use --upgrade to upgrade): pbr==1.8.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 49))
Requirement already satisfied (use --upgrade to upgrade): six==1.9.0 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 51))
Requirement already satisfied (use --upgrade to upgrade): Parsley==1.3 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 52))
Requirement already satisfied (use --upgrade to upgrade): nose==1.3.7 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 53))
Requirement already satisfied (use --upgrade to upgrade): SVGFig==1.1.6 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 54))
Requirement already satisfied (use --upgrade to upgrade): Fabric==1.10.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 57))
Requirement already satisfied (use --upgrade to upgrade): paramiko==1.15.2 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 58))
Requirement already satisfied (use --upgrade to upgrade): ecdsa==0.13 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 59))
Requirement already satisfied (use --upgrade to upgrade): Whoosh==2.4.1+gx1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 66))
Requirement already satisfied (use --upgrade to upgrade): pysam==0.8.4+gx1 in ./.venv/lib/python2.6/site-packages (from -r requirements.txt (line 69))
Requirement already satisfied (use --upgrade to upgrade): importlib in ./.venv/lib/python2.6/site-packages (from kombu==3.0.30->-r requirements.txt (line 40))
Requirement already satisfied (use --upgrade to upgrade): ordereddict in ./.venv/lib/python2.6/site-packages (from kombu==3.0.30->-r requirements.txt (line 40))
You are using pip version 8.0.2+gx2, however version 8.1.1 is available.
You should consider upgrading via the 'pip install --upgrade pip' command.
DEPRECATION: Python 2.6 is no longer supported by the Python core team, please upgrade your Python. A future version of pip will drop support for Python 2.6
Requirement already satisfied (use --upgrade to upgrade): psycopg2==2.6.1 in ./.venv/lib/python2.6/site-packages (from -r /dev/stdin (line 1))
Requirement already satisfied (use --upgrade to upgrade): importlib==1.0.3 in ./.venv/lib/python2.6/site-packages (from -r /dev/stdin (line 2))
Requirement already satisfied (use --upgrade to upgrade): ordereddict==1.1 in ./.venv/lib/python2.6/site-packages (from -r /dev/stdin (line 3))
Requirement already satisfied (use --upgrade to upgrade): drmaa in ./.venv/lib/python2.6/site-packages (from -r /dev/stdin (line 4))
You are using pip version 8.0.2+gx2, however version 8.1.1 is available.
You should consider upgrading via the 'pip install --upgrade pip' command.
Unsetting $PYTHONPATH
Activating virtualenv at .venv
Traceback (most recent call last):
  File "./scripts/paster.py", line 27, in <module>
    serve.run()
  File "/opt/galaxy/lib/galaxy/util/pastescript/serve.py", line 1061, in run
    invoke(command, command_name, options, args[1:])
  File "/opt/galaxy/lib/galaxy/util/pastescript/serve.py", line 1067, in invoke
    exit_code = runner.run(args)
  File "/opt/galaxy/lib/galaxy/util/pastescript/serve.py", line 223, in run
    result = self.command()
  File "/opt/galaxy/lib/galaxy/util/pastescript/serve.py", line 637, in command
    server = loadserver(server_spec, name=server_name, relative_to=base, global_conf=vars)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 303, in loadserver
    return loadobj(SERVER, uri, name=name, **kw)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 319, in loadobj
    global_conf=global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 344, in loadcontext
    global_conf=global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 368, in _loadconfig
    return loader.get_context(object_type, name, global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 502, in get_context
    section)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 524, in _context_from_use
    object_type, name=use, global_conf=global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 454, in get_context
    global_conf=global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 344, in loadcontext
    global_conf=global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 376, in _loadegg
    return loader.get_context(object_type, name, global_conf)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 668, in get_context
    object_type, name=name)
  File "/opt/galaxy/lib/galaxy/util/pastescript/loadwsgi.py", line 688, in find_egg_entry_point
    pkg_resources.require(self.spec)
  File "/opt/galaxy/lib/pkg_resources.py", line 666, in require
    needed = self.resolve(parse_requirements(requirements))
  File "/opt/galaxy/lib/pkg_resources.py", line 565, in resolve
    raise DistributionNotFound(req)  # XXX put more info here
pkg_resources.DistributionNotFound: Paste