Dear Bjoern,

As your suggestion, I tried to install the snpEff annotation. But, I think I am still be stuck there. What I did is:
Admin > Data > Manage local data (beta), then the message is shown as below. (For the BWA and Fetching genome, I installed them from tool_sheds by myself. For the SnpEff staff, it has been there when I checked the data manager.) Next, I clicked on SnpEff Databases > Execute. But, when I checked the snpeff annotations in View managed data by Tool Data Table part, it is still empty. 

Could you give me more details about how to install the annotation with the snpeff data manager under the Admin panel?

I really appreciate for your help, and thank you so much for your patience!

Best,

Xiaofei

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