Hi all,

We were tracking the galaxy master branch on our local server and are looking to migrate to v16.01.

The galaxy processes are managed bij supervisor as shown here ( https://wiki.galaxyproject.org/Admin/Config/Performance/Scaling).

After updating all dependencies in our venv we tried to restart the server but got the following issue:

Loading paste environment: config:/home/galaxy/galaxy-dist/config/galaxy.ini

Traceback (most recent call last):

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 247, in loadapp

    return loadobj(APP, uri, name=name, **kw)

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 271, in loadobj

    global_conf=global_conf)  

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 296, in loadcontext

    global_conf=global_conf)  

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 320, in _loadconfig

    return loader.get_context(object_type, name, global_conf)

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 458, in get_context

    section)

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 517, in _context_from_explicit

    value = import_string(found_expr)

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/paste/deploy/loadwsgi.py", line 22, in import_string

    return pkg_resources.EntryPoint.parse("x=" + s).load(False)

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/pkg_resources/__init__.py", line 2380, in load

    return self.resolve()

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/pkg_resources/__init__.py", line 2386, in resolve

    module = __import__(self.module_name, fromlist=['__name__'], level=0)

  File "lib/galaxy/web/buildapp.py", line 5, in <module>

    from galaxy.webapps.galaxy.buildapp import app_factory

  File "lib/galaxy/webapps/galaxy/buildapp.py", line 15, in <module>

    import galaxy.app

  File "lib/galaxy/app.py", line 9, in <module>

    import galaxy.queues

  File "lib/galaxy/queues.py", line 9, in <module>

    from kombu import Exchange, Queue, Connection

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/kombu/__init__.py", line 67, in __getattr__

    module = __import__(object_origins[name], None, None, [name])

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/kombu/entity.py", line 10, in <module>

    from .abstract import MaybeChannelBound, Object

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/kombu/abstract.py", line 12, in <module>

    from .connection import maybe_channel

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/kombu/connection.py", line 19, in <module>

    from kombu import exceptions

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/kombu/exceptions.py", line 12, in <module>

    from amqp import ChannelError, ConnectionError, ResourceError

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/amqp/__init__.py", line 34, in <module>

    from .connection import Connection      # noqa

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/amqp/connection.py", line 40, in <module>

    from .transport import create_transport

  File "/home/galaxy/galaxy-dist/.venv/lib/python2.7/site-packages/amqp/transport.py", line 21, in <module>

    import ssl

  File "/Shared/Software/Cellar/python/2.7.11/lib/python2.7/ssl.py", line 97, in <module>

    import _ssl             # if we can't import it, let the error propagate

ImportError: /home/galaxy/galaxy-dist/.venv/lib/python2.7/lib-dynload/_ssl.so: undefined symbol: SSL_CTX_set_alpn_protos

So far we have tried:

- rebuilding the venv

- reinstalling python

Funny thing is, when we start the configuration with the “run.sh” script instead of through supervisor everything seems to work just fine.

We’re at a loss, please help!

Thanks!

Matthias

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