Yeah, it definitely looks like the problem is caused by weirdness in your local Python installation. The easiest fix is probably to set up and use a virtualenv for running Galaxy. A compatible version of ctypes should exist as part of the python standard library for your version of python, but my guess is that your system python is using a very old pre-stdlib ctypes module.

One way to figure out which ctypes module is getting used, if you're interested, is to do the following in the python interpreter:

>>> import ctypes

>>> print ctypes.__file__

On Thu, Jun 19, 2014 at 8:28 PM, xlwang <xlwang_0903@163.com> wrote:

Thank you for your reply.
my python is 2.7.3 and I didn't use virtualenv. But I used and learned galaxy since 2012, it runs well until i installed a new instance a few days ago.

when I run these python commands ,some errors occurred:
>>> import ctypes
>>> ctypes.CDLL('librt.so.1',use_errno=True)
Traceback (most recent call last):

File "<stdin>", line 1, in <module>
TypeError: __init__() got an unexpected keyword argument 'use_errno'
>>>

Is the problem caused by python?

At 2014-06-19 08:12:10, "Dannon Baker" <dannon.baker@gmail.com> wrote:

I still haven't been able to reproduce this and am not sure what is wrong. What exact version of python are you running? Are you using a clean python environment -- virtualenv?

Can you open a python terminal and try these commands manually?

>>> import ctypes
>>> ctypes.CDLL('librt.so.1', use_errno=True)

It *should* work, yielding you something like:

<CDLL 'librt.so.1', handle 1f397b0 at 7ff73c261910>

On Wed, Jun 18, 2014 at 10:49 PM, xlwang <xlwang_0903@163.com> wrote:

Hello,
I got an error when I installed and started a new galaxy instance just now. And I have an old version galaxy instance, it can be started and runs well, but when I updated it, the old one will get the same error like the following picture:

please help me and tell me how to fix it, thank you very much!

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