Hi, I am trying to setup a local production Galaxy running on Ubuntu, Nginx, PostgreSQL, and ProFTD. When visiting http://localhost, "502 Bad Gateway" is returned. Visiting https://localhost returns "unable to connect". I was expecting to see the Galaxy website instead. My Nginx configuration file is included below. Thank you for your help. ########################### # /etc/nginx/nginx.conf ########################### user www-data; worker_processes 4; pid /run/nginx.pid; events { worker_connections 768; # multi_accept on; } http { ## # Basic Settings ## sendfile on; tcp_nopush on; tcp_nodelay on; keepalive_timeout 65; types_hash_max_size 2048; # server_tokens off; # server_names_hash_bucket_size 64; # server_name_in_redirect off; include /etc/nginx/mime.types; default_type application/octet-stream; ## # Logging Settings ## access_log /var/log/nginx/access.log; error_log /var/log/nginx/error.log; ## # Gzip Settings ## gzip on; gzip_http_version 1.1; gzip_vary on; gzip_comp_level 4; gzip_proxied any; gzip_types text/plain text/css application/x-javascript text/xml application/xml text/javascript application/json; gzip_buffers 16 8k; gzip_disable "MSIE [1-6].(?!.*SV1)"; ## # nginx-naxsi config ## # Uncomment it if you installed nginx-naxsi ## #include /etc/nginx/naxsi_core.rules; ## # nginx-passenger config ## # Uncomment it if you installed nginx-passenger ## #passenger_root /usr; #passenger_ruby /usr/bin/ruby; ## # Virtual Host Configs ## include /etc/nginx/conf.d/*.conf; #include /etc/nginx/sites-enabled/*; ## # Galaxy ## upstream galaxy_app { # As defined in galaxy config file universe_wsgi.ini server localhost:8080; server localhost:8081; server localhost:8082; server localhost:8083; server localhost:8084; server localhost:8085; server localhost:8086; server localhost:8087; server localhost:8088; server localhost:8089; } server { # Maximum upload size that can be handled by POST requests through nginx. # Disabled because using FTP instead of web interface. #client_max_body_size 10G; location / { proxy_pass http://galaxy_app; proxy_set_header X-Forwarded-Host $host; proxy_set_header X-Forwarded-For $proxy_add_x_forwarded_for; # If using SSL, makes Galaxy aware of what type of URL it should generate for external sites like Biomart. proxy_set_header X-URL-SCHEME https; } # nginx is more efficient at serving static content. # expires 24h is for caching purposes. location /static { alias /home/galaxy/galaxy-dist/static; expires 24h; } location /static/style { alias /home/galaxy/galaxy-dist/static/june_2007_style/blue; expires 24h; } location /static/scripts { alias /home/galaxy/galaxy-dist/static/scripts/packed; } location /favicon.ico { alias /home/galaxy/galaxy-dist/static/favicon.ico; } location /robots.txt { alias /home/galaxy/galaxy-dist/static/robots.txt; } # Use nginx to send files (downloads) instead of Galaxy. location /_x_accel_redirect/ { internal; alias /; } } } ########################### # /var/log/nginx/error.log ########################### 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8089/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8080/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8081/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8082/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8083/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8084/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8085/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8086/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8087/", host: "localhost" 2014/11/25 15:43:21 [error] 56433#0: *23 connect() failed (111: Connection refused) while connecting to upstream, client: 127.0.0.1, server: , request: "GET / HTTP/1.1", upstream: "http://127.0.0.1:8088/", host: "localhost"