Hello, I have a general question. A metagenome prediction in PICRUSt worked fine when I ran it requesting KEGG output (running on MAIN), but I got the below error when requesting COG output. I could not find in the on-line forums or other areas of support what may be needed regarding a different input file or change in the normalization by copy number in order to get COG instead of KEGG output? Thank you very much for your help! Ana Traceback (most recent call last): File "/n/galaxy/www/galaxy_hutlab14/galaxy-hutlab14-20150109/tools/picrust_galaxy/scripts/predict_metagenomes.py", line 337, in <module> main() File "/n/galaxy/www/galaxy_hutlab14/galaxy-hutlab14-20150109/tools/picrust_galaxy/scripts/predict_metagenomes.py", line 171, in main ids_to_load=ids_to_load,verbose=opts.verbose,transpose=True) File "/n/galaxy/www/galaxy_hutlab14/galaxy-hutlab14-20150109/tools/picrust_galaxy/scripts/predict_metagenomes.py", line 113, in load_data_table genome_table_fh = gzip.open(data_table_fp,'rb') File "/n/hutlab11/tools/python2.7.8/lib/python2.7/gzip.py", line 34, in open return GzipFile(filename, mode, compresslevel) File "/n/hutlab11/tools/python2.7.8/lib/python2.7/gzip.py", line 94, in __init__ fileobj = self.myfileobj = __builtin__.open(filename, mode or 'rb') IOError: [Errno 2] No such file or directory: '/usr/local/galaxy-python/lib/python2.7/site-packages/picrust/data/cog_13_5_precalculated.tab.gz'