Hi Everyone, I was just using my local galaxy instance. I closed it up (from terminal), open IGV to look at some genes, then I restarted it from the terminal and when I tried to access it I got the error message below. I just don't know what happened in these few minutes. Any suggestion how to fix it? Thank you. Luciano URL: http://127.0.0.1:8080/ File '/home/koala2/galaxy-central/eggs/WebError-0.8a-py2.7.egg/weberror/evalexception/middleware.py', line 364 in respond app_iter = self.application(environ, detect_start_response) File '/home/koala2/galaxy-central/eggs/Paste-1.6-py2.7.egg/paste/debug/prints.py', line 98 in __call__ environ, self.app) File '/home/koala2/galaxy-central/eggs/Paste-1.6-py2.7.egg/paste/wsgilib.py', line 539 in intercept_output app_iter = application(environ, replacement_start_response) File '/home/koala2/galaxy-central/eggs/Paste-1.6-py2.7.egg/paste/recursive.py', line 80 in __call__ return self.application(environ, start_response) File '/home/koala2/galaxy-central/eggs/Paste-1.6-py2.7.egg/paste/httpexceptions.py', line 632 in __call__ return self.application(environ, start_response) File '/home/koala2/galaxy-central/lib/galaxy/web/framework/base.py', line 160 in __call__ body = method( trans, **kwargs ) File '/home/koala2/galaxy-central/lib/galaxy/web/controllers/root.py', line 25 in index m_c=m_c, m_a=m_a ) File '/home/koala2/galaxy-central/lib/galaxy/web/framework/__init__.py', line 733 in fill_template return self.fill_template_mako( filename, **kwargs ) File '/home/koala2/galaxy-central/lib/galaxy/web/framework/__init__.py', line 744 in fill_template_mako return template.render( **data ) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/template.py', line 296 in render return runtime._render(self, self.callable_, args, data) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 660 in _render **_kwargs_for_callable(callable_, data)) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 691 in _render_context (inherit, lclcontext) = _populate_self_namespace(context, tmpl) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 637 in _populate_self_namespace ret = template.module._mako_inherit(template, context) File '/home/koala2/galaxy-central/database/compiled_templates/root/ index.mako.py', line 25 in _mako_inherit return runtime._inherit_from(context, u'/webapps/galaxy/base_panels.mako', _template_uri) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 609 in _inherit_from ret = callable_(template, lclcontext) File '/home/koala2/galaxy-central/database/compiled_templates/webapps/galaxy/ base_panels.mako.py', line 25 in _mako_inherit return runtime._inherit_from(context, u'/base_panels.mako', _template_uri) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 596 in _inherit_from template = _lookup_template(context, uri, calling_uri) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/runtime.py', line 626 in _lookup_template return lookup.get_template(uri) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/lookup.py', line 218 in get_template return self._load(srcfile, uri) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/lookup.py', line 283 in _load **self.template_args) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/template.py', line 218 in __init__ module = self._compile_from_file(path, filename) File '/home/koala2/galaxy-central/eggs/Mako-0.4.1-py2.7.egg/mako/template.py', line 245 in _compile_from_file module = imp.load_source(self.module_id, path, open(path, 'rb')) IOError: [Errno 13] Permission denied: u'/home/koala2/galaxy-central/database/compiled_templates/ base_panels.mako.py'