[galaxy-dev] requested number of bytes is more than a Python string can hold

one of our users is experiencing this error from the SAM-to-BAM tool: Error extracting alignments from (/hpcdata/galaxy-setup/galaxy-dist/database/files/000/dataset_85.dat), requested number of bytes is more than a Python string can hold The SAM file has 58 million lines of mapped paired end reads. Any suggestions? The galaxy jobs running on our cluster are currently using the version of Python installed with CentOS 5 (python 2.4.3, 64-bit). We have been considering setting up a new python virtualenv for the galaxy user on the cluster that uses a newer version of Python (probably 2.6 so it matches the version on the server running the galaxy web app) -- Glen L. Beane Software Engineer The Jackson Laboratory Phone (207) 288-6153