Dear all, I'm still new to Galaxy but was wondering if someone could offer some advice. On a local Galaxy instance, if I were the Galaxy administrator but do not have sudo access on the machine itself, is this a problem? Or are the two roles intricately linked so that the Galaxy administrator will have to pester the system administrator frequently? The web interface alone is not sufficient for the Galaxy administrator. (i.e., does a Galaxy administrator need sudo access ... or even just group access to the Galaxy subdirectory to effectively do his/her job? ...I mean making Galaxy owned by a Unix group and putting the Galaxy administrator in that group.) As an aside, I was trying to do some alignment with bwa and realized I needed to prepare the genome by creating the index and an accompanying .loc file. The instructions [1] seem to imply some kind of command-line access.. Thank you for your help! Ray [1] https://wiki.galaxyproject.org/Admin/DataPreparation