Hi, I am seeing this in the log files when I start up... It seems to identify a name error in the file update_manager.py I am not sure if it is related, but some of my manager processes are just dying without any errors in the log...The processes are just killed (The PID is just gone, so run.sh --stop_daemon tells me they are not valid).... I did notice that python library is /usr/lib64/python2.6/threading.py, but I am using a virtual_env installation so I would have assumed it would have been using the lib64 stuff in my virtual_env environment, but then again, there is no file threading.py in that library so I guess it is not making a complete copy of all the files... In any case, my galaxy system is very unstable, so any help would be appreciated... Thon galaxy.tool_shed.update_manager INFO 2013-01-19 12:19:02,167 Update manager restarter starting up... Exception in thread Thread-1: Traceback (most recent call last): File "/usr/lib64/python2.6/threading.py", line 532, in __bootstrap_inner self.run() File "/usr/lib64/python2.6/threading.py", line 484, in run self.__target(*self.__args, **self.__kwargs) File "/mnt/ngs/analysis/svcgalaxy/galaxy-dist/lib/galaxy/tool_shed/update_manager.py", line 25, in __restarter .filter( and_( self.app.model.ToolShedRepository.table.c.update_available == False, NameError: global name 'and_' is not defined galaxy.datatypes.registry DEBUG 2013-01-19 12:19:02,175 Loaded display application 'ucsc_bam' for datatype 'bam', i