Hi Jochen,

You might want to enable the heartbeat (see the relevant options in galaxy.ini), so you can see what the threads are actually doing during that period. This should give you some insight on the culprit.

--nate

On Mon, Dec 12, 2016 at 9:40 AM, Jochen Bick <jochen.bick@usys.ethz.ch> wrote:
Thanks for your reply but in my case it did not solve the problem...
has anyone else good ideas to speed up galaxy?

Cheers Jochen

On 09.12.2016 17:07, Hendrickson, Curtis (Campus) wrote:
> Jochen
>
> We once had a similar, sudden performance problem, and found that the setting
>
>       Galaxy.ini: debug = False
>
> Had accidentally been re-set to "True". Having "debug" turned on really, really slows down the galaxy app process....
>
> So, check that debug = False.
>
> Regards
> Curtis
>
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