Yes, it decompresses them during import. On Dec 18, 2012, at 1:28 PM, Fenglou Mao <fenglou@gmail.com<mailto:fenglou@gmail.com>> wrote: Is Galaxy capable of working with compressed files such as *.fastq.gz? Thanks, Fenglou ___________________________________________________________ Please keep all replies on the list by using "reply all" in your mail client. To manage your subscriptions to this and other Galaxy lists, please use the interface at: http://lists.bx.psu.edu/ -- Brad Langhorst langhorst@neb.com<mailto:langhorst@neb.com>