Hi, I've follow the instruction of this wiki : http://wiki.g2.bx.psu.edu/Admin/Config/Performance/Web%20Application%20Scali... And when I ran the command : GALAXY_RUN_ALL=1 sh run.sh --daemon I've just obtain this answer in the terminal : Entering daemon mode without this type of line : Handling web0 with log file web0.log First : is it normal and is my apache configuration right : In my Default file I add <Proxy balancer://galaxy>... after my rewrite rules and it replace the instructions :<Proxy http://localhost:8080>... Second : how can I connect in my browser to Galaxy, because I've tried http://localhost:8080/galaxy and http://localhost:8079/galaxy and it didn't work, the browser says me : unable to connect I set this configuration because I want to increase the performances of Galaxy. in fact when I upload a file, with your web server, it run in 20 minutes and with my server it don't finish after 1 hour! Is it normal? Thank you for your attention. julie