input file:

chr2   230341630  +  G/A
chr2   43881517   +  A/T
chr10  115912482  -  G/T
chr10  115900918  -  C/T

output file:

#Chrom  Position   Strand  Allele  Codons   Transcript ID    Protein ID       Substitution  Region    dbSNP ID      SNP Type       Prediction  Score  Median Info  Num seqs at position  User Comment
chr2    230341630  +       G/T     -        ENST00000389045  ENSP00000373697  NA            EXON CDS  rs1803846:A   Unknown        Not scored  NA     NA           NA
chr2    43881517   +       A/T     ATA-tTA  ENST00000260605  ENSP00000260605  I230L         EXON CDS  rs11556157:T  Nonsynonymous  TOLERATED   0.47   3.19         7
chr10   115912482  +       C/A     CGA-CtA  ENST00000369285  ENSP00000358291  R179L         EXON CDS  rs12782946:T  Nonsynonymous  TOLERATED   0.06   4.32         2
chr10   115900918  +       G/A     CAA-tAA  ENST00000369287  ENSP00000358293  Q271*         EXON CDS  rs7095762:T   Nonsynonymous  N/A         N/A    N/A          N/A