Hello,

 

I'm not sure if this is the place to ask this, but if so - here goes.   If I have a list of genomic regions (from CNV gains and losses) comprised of chromosome, start and stop (ie. chr7    68000000       71000000) for a given genome build (HG 18), and I want to add the genes (ideally HUGO gene Symbols or refseqIDs)that reside within each region per line. 

 

So I want to input something like this:

 

Sample

Chromosome Region

Event

Length

JC 507 CD19

chr10:11,997,707-12,330,274

CN Gain

332568

JC 507 CD19

chr10:47,563,503-48,085,608

CN Loss

522106

JC 507 CD19

chr10:69,510,584-69,951,738

CN Gain

441155

 

And get an output similar to this:

 

Sample

Chromosome Region

Event

Length

Gene Symbols

JC 507 CD19

chr10:11,997,707-12,330,274

CN Gain

332568

CDC123, DHTKD1, NUDT5, SEC61A2, UPF2

JC 507 CD19

chr10:47,563,503-48,085,608

CN Loss

522106

AGAP9, ANXA8, ANXA8L1, CTSL1P2, FAM25B, FAM25C, FAM25G, GDF10, GDF2, LOC642826, RBP3, ZNF488

JC 507 CD19

chr10:69,510,584-69,951,738

CN Gain

441155

ATOH7, DNA2, HNRNPH3, MYPN, PBLD, RUFY2, SLC25A16

 

 

Possible ?

 

 

Shawn Anderson

Application Scientist - Laboratory for Advanced Genome Analysis

Vancouver Prostate Centre - Vancouver General Hospital

2660 Oak Street

Vancouver BC V6H 3Z6

P:604-875-4111 ext. 63436

F:604-875-5654

sanderson@prostatecentre.com

www.LAGAPC.ca

 



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