Hello, I am resending this since it seemed to have gotten lost in the moderation queue somewhere. I am using a local install of galaxy for processing Illumina data. However, for large (about 3 GB) files, it gives an error and while it appears as if the upload is progressing, nothing happens. File "/home/lin/public_html/galaxy-dist/eggs/WebOb-0.8.5-py2.6.egg/webob/__init__.py", line 818, in str_POST keep_blank_values=True) File "/usr/lib64/python2.6/cgi.py", line 508, in __init__ self.read_multi(environ, keep_blank_values, strict_parsing) File "/usr/lib64/python2.6/cgi.py", line 635, in read_multi headers = rfc822.Message(self.fp) File "/usr/lib64/python2.6/rfc822.py", line 108, in __init__ self.readheaders() File "/usr/lib64/python2.6/rfc822.py", line 155, in readheaders line = self.fp.readline() File "/usr/lib/python2.6/site-packages/paste/httpserver.py", line 476, in readline data = self.file.readline(max_read) File "/usr/lib64/python2.6/socket.py", line 379, in readline bline = buf.readline(size) OverflowError: signed integer is greater than maximum ---------------------------------------- 127.0.0.1 - - [13/Apr/2010:12:14:00 +0600] "GET /history HTTP/1.1" 200 - " http://localhost:8080/tool_runner/upload_async_message" "Mozilla/5.0 (X11; U; Linux x86_64; en-US) AppleWebKit/533.2 (KHTML, like Gecko) Chrome/5.0.342.7 Safari/533.2" ==== End of error output=== What could be going wrong? Thanks. Any help would be appreciated. Lin