Hello. I am trying to set up a copy of Galaxy on my local SuSe Linux machine. I have it running on localhost. I get the following error message when trying to get the genomic sequences for a set of coordinates: "error, format: fasta,database: hg17 Info: Cannot open /depot/data1/cache/alignseq.loc No such file or directory" I'm guessing that the program assumes a certain directory structure to be in place (including a path called /depot/data1/cache). Just wondering if there are other directories I will need to create to get this system running smoothly. I could not find any documentation regarding this on the Galaxy setup page. If such documentation exists, I would be very appreciative if you could point me towards it. Regards. Ryan P.S. Great application nonetheless!