Hello, The cloud version of Galaxy is quite easy to fire up and is very complete with all tools and genomes preinstalled. Local installation on the other hand is painful, contrary to the nice descriptions among the wiki pages. For exmples, see this: http://vallandingham.me/installing_galaxy_tools.html The initial install of galaxy is easy enough, but making a complete setup is quite painful without dedicated IT people. Setting up ftp server access for uploading and installing tool dependencies in particular are not pleasant. Since the cloud version comes with everything including the kitchen sink, would it be possible to create a more compete local install bundle that also includes everything, without resorting to running a VM locally? Have I missed some other really easy process? Thanks, Jim