Hi, For those who use snpEff V3_3c release in Galaxy. There are two little bugs in snpSiftWrapper.pl. You can find the corrected file in the attachment. Best Regards, -- Yufei LUO Bioinformatician Insitut Gustave Roussy Bâtiment de Médecine Moléculaire Bureau N°136 114, rue Edouard Vaillant 94805 Villejuif Cedex - France