Hello, I found Galaxy extremely helpful in the past months and I have an issue that could again be solved using your wonderful platform. I am playing with a bunch of sequences (genome coordinates) from the human genomes that I obtained from some blast searches. I would like to see if these exact sequences are shared by (in synteny with) chimp, orang and macaque. I got MAF blocks from Galaxy and played with them, but I don't see an easy solution. It would be great if you have some suggestion about how to work with synteny using Galaxy, if possible. Thanks a lot! Claudio Casola Postdoctoral fellow, Hahn Lab Department of Biology 1001 East Third Street Bloomington, IN 47405-3700 Indiana University 812-856-7016 ccasola@indiana.edu