On Thu, Sep 29, 2011 at 7:49 PM, Cecilia Tamborindeguy
I would like to know if Galaxy can do de novo assembly without a reference
Are you trying to use the Public Galaxy or a local install? There
are several assemblers with Galaxy Wrappers on the Galaxy
ToolShed (e.g. Roche "Newbler", and MIRA 3) which you could
add to your own local Galaxy if you have one.
However, do novo genome assembly can be very computationally
demanding, so not many Galaxy Instances will want to offer it.