Simon,
Error executing tool: (ProgrammingError) column "params" of relation "job" does not exist
This is your problem. This column should have been created in migration script 93, but for some reason it wasn't. The first step is to determine if subsequent migration scripts failed as well. Run this query against your Galaxy database: SELECT * FROM migrate_version; What is the version? Also, for completeness, what database are you using? Something else you can try is downgrading your database revision and then upgrading to see if you can find the problem. From a command line in your galaxy directory, do this: % sh manage_db.sh downgrade 92 % sh manage_db.sh upgrade You may want to back up your database before trying anything to ensure that you can rollback if something goes wrong. J.