[galaxy-user] Pseudo Autosomal regions in Chrs X and Y

Hi All again,

A separate point about the analysis of cufflinks data is the subject of the Pseudo Autosomal Regions in X and Y - this will make a mess of gene expression analysis in some cases especially because tophat will assign a read to both places which therefore makes it a multihit read (which you might then filter out) or it may double the true levels of reported expression. Anyone had experience/thoughts on this?

Best Wishes, David.

__________________________________ Dr David A. Matthews

Senior Lecturer in Virology Room E49 Department of Cellular and Molecular Medicine, School of Medical Sciences University Walk, University of Bristol Bristol. BS8 1TD U.K.

Tel. +44 117 3312058 Fax. +44 117 3312091

D.A.Matthews@bristol.ac.uk