September 2025 - galaxy-proteomics - lists.galaxyproject.org

TOPPview in Galaxy
by Martin Hubálek 13 Nov '25

13 Nov '25

Hi, I would like to get an advice on using OpenMS in Galaxy, especially on connecting TOPPview to visualize the results. Can anyone help me? Thanks, Martin -- Martin Hubálek, Ph.D. Institute of Organic Chemistry and Biochemistry, CAS Flemingovo nám. 2, 16610 Praha 6, Czech Republic tel.: 220183117

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Slope 2 – Speed, Skill, and Gravity in Perfect Sync
by florevernon19＠gmail.com 21 Oct '25

21 Oct '25

Slope 2 is an addictive 3D endless running game where you control a fast-rolling ball on a neon-lit track full of sharp turns, steep slopes, and deadly drops. With sleek graphics and responsive controls, the game challenges your reflexes as the speed increases the longer you survive. The physics are smooth and dynamic, making each run feel intense and unpredictable. You’ll need lightning-fast reaction time to dodge obstacles and stay on the track. It’s simple to pick up but hard to master — perfect for quick breaks or long sessions. Slope 2 also features leaderboard rankings, pushing players to beat their best distance. No downloads, no sign-ups — just straight into the action in your browser. Ideal for both casual gamers and speedrun enthusiasts. A modern arcade classic that keeps your heart racing. Try it once, and you’ll be hooked. https://slope2game.io

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Doodle Baseball: A Charming, Snack-Sized Swing Through Google’s Tiny Classic
by joint.lion.dmqp＠rapidletter.net 17 Oct '25

17 Oct '25

If you remember the days when the web was a playground of tiny wonders, you might recall a July 4th Doodle that turned snacks into ballplayers. I kept coming back to that goofy, endearing universe where pretzels steal bases and churros slide into home like they own the plate. This isn’t just a game; it’s a pocket of nostalgia you can dip into for a quick bite of joy. Let’s swing into why this little browser gem still sticks with me—and why it might just win you over, too. What makes Doodle Baseball unique? Playful art style: The moment you load it up, you’re greeted by a cast of anthropomorphic snacks in bright, friendly colors. It feels handmade, almost doodled in a notebook, which somehow makes every pitch feel personal. The art is cozy, not polished to death, and that charm becomes the whole point. Food characters: Imagine a lineup where a confident hot dog stands at the plate while a smug slice of pizza mans the mound. The characters aren’t just cute; they bring a wink to the action. Their little animations—twitching whiskers, wobbly bats, and tiny confetti bursts—make each moment feel like a fond memory rather than a high-stakes tournament. Simple gameplay: It’s not a blockbuster simulator; it’s a browser mini-game that respects your time. Expect intuitive controls, short rounds, and enough tension to keep you hooked without a steep learning curve. You swing, the computer pitches, you react, and you either cheer or groan in good fun. Surprising addictiveness: The bastardized perfection of a pick-up-and-play arcade loop is real here. You’ll jot down a quick score, then realize you’re chasing a better number than your last visit. The quick sessions add up, and before you know it you’ve burned through a few snack breaks in one afternoon—indulgent, lighthearted, and oddly satisfying. Real gameplay experience & funny moments I’ll spare you the pretend-mastery fantasy: I’ve definitely donoed into the game with the confidence of a steady hand at a carnival game and walked away with nothing but a smile. A few moments that stand out: The first swing you take and miss by a mile, then realize the arc of the ball feels like it’s teasing you—like the doodles are winking. You laugh, adjust, and then finally connect on a crusty, deliciously imperfect hit. When a hot dog steals second base and slides into home after a wobble of the screen, the crowd sound effect erupts in a goofy chorus. It’s silly, but that silliness nails the vibe: playful, not punishing, and somehow elevates a simple sport into a tiny celebration. The unexpected home run by a cinnamon roll—yes, a cinnamon roll—lands with an over-the-top puff of confetti. You cheer louder than you expected, because it isn’t just a win; it’s a tiny artful moment that feels crafted for smiles. The sound design is a star here: light pops, crunchy bat sounds, and those soft “thud” notes when you miss. It’s like a pleasantly awkward skate video soundtrack for your fingers. The pacing is slyly perfect. Short rounds mean you can squeeze a few innings into a coffee break without losing track of the day, which makes it ideal for a quick, mood-lifting reset. If you’ve ever chased a perfect run in a game that isn’t trying to be serious, you know that feeling when you finally time the pitch and your character glides through the sweet spot. That moment is what keeps pulling you back—the little sense that you’re part of a tiny, cheerful, perfectly imperfect world. FAQ How to play Doodle Baseball today? You’ll want to search for the original doodle or a reliable recreation that runs in a modern browser. The experience is browser-based, so there’s usually no download needed. Look for a lightweight, safe version hosted on reputable platforms or archives. Once loaded, the controls are simple: time your swing to the pitch, aim for the sweet spot, and enjoy the quick rounds that follow. Is Doodle Baseball an official Google game? It originated as a Google Doodle, which gives it that authentic, nostalgic vibe. Over time, there have been recreations and community adaptations. If you’re curious about the lineage, check for notes on the page you’re playing from—authentic Doodles typically carry clear branding or archival references. Can kids play Doodle Baseball safely? Yes. The game is simple, non-graphic, and designed for quick joy. As with any online play, it’s wise to supervise younger users and steer them toward trusted sources if you’re sharing a link. The content stays light, goofy, and family-friendly, which makes it a nice, approachable pick for kids. Conclusion with CTA This little baseball world tucked among doodles reminds me how playful the internet used to be—and how a simple, well-made moment can spark real smiles. If you’ve got a spare minute, give it a swing and see which snack character becomes your MVP. I’d love to hear your score and your favorite food character. https://doodlebaseballgame.com

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Mailing list moved, but not to Google Groups
by Dave Clements 24 Sep '25

24 Sep '25

Hello all, This mailing list has a new home! But it isn't Google Groups. Yesterday Nate moved this list from the lists.bx.psu.edu domain to the lists.galaxyproject.org domain. This gives us better control over the list, including spam. This transition should be largely transparent to you, but there are a few things to be aware of: - List sender addresses and headers will change to reflect the updated domain: from bx.psu.edu togalaxyproject.org. Existing email filters you have set up may require adjustments. - Posts from lists.galaxyproject.org could be categorized as spam until you train your filtering method. - Mailing list archives and posting functionality will be briefly inaccessible during the migration. - The prior bx.psu.edu list posting email addresses will continue to accept email, which will be forwarded to the new list addresses. What happened to the Google Groups plan, you might ask. Well, we used Google Groups for the GCC2014 mailing lists and they were problematic. It turns out that many people's work email servers periodically identify Google Groups as a spammer and then just block it causing emails from the list to silently stop being delivered. Not exactly the behavior you want in a mailing list. Please let us know if you have any questions. Thanks, Dave C and Nate On Thu, May 22, 2014 at 12:17 PM, Dave Clements <clements(a)galaxyproject.org> wrote: > Hello Galaxy Proteomicists! > > The Galaxy Project has started to create new mailing lists using a Google > Groups infrastructure. The new lists still work like mailing lists (plus > other stuff). We are hoping that Google Groups proves to be less > maintenance than Mailman. We are also considering moving our established > lists to Google too. > > Since this is the smallest and least active of the Galaxy community's > mailing lists, this is the first established list we are going to move. > Look for this to happen before GCC2014. > > If anyone has any requests or questions about the move, please let us know. > > Thanks, > > Dave C > > PS: John Chilton originally wanted this list set up on Google Groups. I > talked him out of it. There can't possibly be a lesson for me in that > experience, can there? ;-) > -- http://galaxyproject.org/ http://getgalaxy.org/ http://usegalaxy.org/ https://wiki.galaxyproject.org/

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Flappy Bird: A Spark of Sunshine in a Tiny Pixel World
by substantial.shrew.otol＠rapidletter.net 09 Sep '25

09 Sep '25

I warmed up with a quick tap and expected a headache, but what I got was a carnival of tiny triumphs. A beak, a chorus of chirps, and pipes that turn every blink into a giggle. This is the kind of cheerful chaos that sticks with you—the little moments that remind you joy can come from the simplest taps. What makes Flappy Bird stand out? Playful, lighthearted mechanics: Tap to flap, dodge pipes, and ride a rhythm that feels like gravity is clapping along. Retro charm with upbeat energy: Classic visuals meet a mood that’s bright, silly, and surprisingly uplifting. A mischievous difficulty arc: Kind at first, then cheekily tricky—each miss invites another go with a bigger grin. A spectrum of reactions, all grounded in fun: Giddy bragging, goofy disbelief, and friendly banter mark the boundary between competition and camaraderie. Real gameplay experience & tips (the sunny, pragmatic kind) confession time: early attempts were a goofy scramble of overshoots and surprised gasps, yet those mishaps turned into light-hearted punchlines we shared. That vibe kept me playing, because every crash felt like a joke that wants a rerun. Frustrations: The itch to press harder after a near-miss, only to mis-time the tap in a playful way. Rogue gaps that pop up to test your swagger and rhythm. Wins: The moment taps click into a smooth glide, and the bird feels almost proud to be in the air. Navigating two pipes with a cheeky grin and a little wink to yourself. Fun hacks: Start with a tiny, goofy warm-up for your thumbs to loosen the mood. Sit comfortably, wrists relaxed, posture loose—comfort keeps the laughter going longer. Narrate your blooper reel aloud; humor turns stumbles into shared stories. Personal moment: a friendly group challenge turned into a chorus of goofy voices for the bird and a playlist that made every crash feel like a mini sketch. No records, just pure, contagious joy. FAQ How to play Flappy Bird on PC? There’s no official modern download from the original publisher. Look for reputable unofficial ports or browser versions that mimic the tap-to-flap feel. Prioritize safety and copyright. Is Flappy Bird still available to download? The original app was removed years ago. Fan remasters exist, but the exact official version isn’t common in stores. Seek licensed variants that capture the mood without rights issues. Is Flappy Bird suitable for kids? Quick to pick up and cheerful, great for light play. The difficulty can surprise younger players, so supervision and short sessions help keep it joyful. Conclusion with CTA There’s a bright spark in a tiny bird zigzagging through pipes, turning crashes into chuckles and small wins into stories you’ll tell again soon. If you’re craving a quick, sunny reset, give it another go and watch the goofy magic unfold. I’d love to hear your funniest moments, your silliest near-misses, or your celebratory mini-wins. https://flappybird2d.com

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