I have a list of variants(SNPs) that differ from reference sequence (in my human subject DNA) and I want to filter out the known variants reported in dbSNP, so that I can have a short list of putative novel variants. Could somebody please tell me how can I do this?
Atteeq Ur Rehman
National Institute on Deafness and Other Communication Disorders,
National Institutes of Health,
Room 2A-19, 5 Research court, Rockville, MD, USA, 20850.
Lab Ph. No. 301-402-9059